MicroRNAs (miRNAs) are small non-coding RNAs that can regulate gene expression and that are frequently altered in human cancers. Computational approaches can help us understand how miRNAs are dysregulated and potentially offer new therapies.
The goal of the CTD2 Network is to understand how tumor heterogeneity leads to drug resistance in order to develop optimal combinations of chemotherapy or small molecules in combination with immunotherapy.
From the analysis of over 11,000 tumors from 33 of the most prevalent forms of cancer, the Pan-Cancer Atlas provides a uniquely comprehensive, in-depth, and interconnected understanding of how, where, and why tumors arise in humans.
The ISB Cancer Genomics Cloud (ISB-CGC) is democratizing access to NCI Cancer Data and coupling it with unprecedented computational power to allow researchers to explore and analyze this vast data-space.